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Antithyroid goitrogens and hypothyroidism – Goitrogens, Thyroid Disease, and Your Diet

Spinach, okra, sweet potato, elderberry, figs, leeks, buckwheat, celery, other leafy greens, and dandelions are some sources.

William Thompson
Tuesday, September 3, 2019
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  • Thyroid hormones help control growth, cell repair, and metabolism. The sources were selected based on pre-searches and includes American, European as well as global publications.

  • Minimizing Effects. Iodine, thiocyanate and the thyroid.

  • This article will provide an overview of thyroid disease, its relationship with cardiovascular disease and diabetes, and the role nutrition plays in maintaining thyroid health.

  • Steaming crucifers until fully cooked reduces goitrogens by two-thirds. The association between soya consumption and serum thyroid-stimulating hormone concentrations in the Adventist Health Study

Cruciferous vegetables and other foods can affect your thyroid

Please help improve it or discuss these issues on the and hypothyroidism page. Sign Up. Efficacy and safety of short-term genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial. Another study published recently comparing soy protein and casein protein without soy isoflavones in patients with subclinical hypothyroidism reported no significant changes in thyroid function Biochem Pharmacol 54—

Nonetheless, if you have hypothyroidism, aim to eat more zinc-rich foods like oysters and other shellfish, beef, and chicken. Vegan sources include fortified cereals and nutritional yeast. Duval, S. Cooksey; Jim Legan; Edward F.

In a study of Boston mothers, 47 percent of breast milk samples did not have sufficient levels of iodine Facebook 0 Tweet 0 Pin 0. Goitrogens are not an outright death sentence for kale and broccoli. Natural Treatment Options for Hypothyroidism. Substances Antithyroid Agents. Publication types Research Support, Non-U.

Introduction

Publication types Research Support, Non-U. After reading this article, I am leaning towards goitrogens. Goitrogenic foods are rich in vitamins and minerals, and most experts do not recommend that anyone—including patients with thyroid disease—avoid eating them.

  • PMID Effect of cooking brassica vegetables on the subsequent hydrolysis and metabolic fate of glucosinolates.

  • At relatively low concentrations, goitrogens decrease the uptake of iodine by the thyroid gland. Substances Antithyroid Agents.

  • Foods that contain some vitamin D include fatty fish, milk, dairy, eggs, and mushrooms.

  • Table of Contents View All. Flavonoids in foods can be also be converted into goitrogenic compounds by bacteria that exist in the gut.

  • This signal is sent from the pituitary gland, a small gland found at the base of your brain, when thyroid hormone levels are low 4. Read this next.

Do you think that lowering or doing a goitrogen detox might help with the chronic fatigue and brain fog? Iodine, thiocyanate and the hypohtyroidism. Various possible toxicants involved in thyroid dysfunction: a review. Abstract A large number of agents in the environment and some medications are known to interfere with thyroid gland function, posing the danger of thyroid disease. If someone is already iodine-deficient, then goitrogens are more likely to cause issues. At present, medical or surgical treatments for the individual, but not measures for prevention and control at community level, are being applied in iodine-sufficient goitre areas.

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Canaris, G. However, this only seems to be an issue for people who have an iodine deficiency or eat large amounts of goitrogens 222324 The thyroid hormone helps control the speed of your metabolism. Hyperthyroidism, or overactive thyroid gland, is another common thyroid condition. Effect of soy isoflavones on breast cancer recurrence and death for patients receiving adjuvant endocrine therapy. Annual Review of Nutrition. Limitations of the present meta-analysis include the fact that the pooled population analysed in this meta-analysis included a limited number of subjects because the sample size in some of the clinical trials was small, and the treatment duration of many of the trials was short.

Your metabolism affects your body temperature and at what rate you burn calories. Tying It Altogether Thyroid disease presents unique antituyroid due to undesired weight changes, significant cardiovascular risks, and symptoms such as fatigue, mood changes, and gastrointestinal upset, which can hinder the development of healthful behaviors. Soy isoflavones exert modest hormonal effects in premenopausal women. A dictionary of food and nutrition 3rd ed.

Publication types

Nonetheless, if you have hypothyroidism, aim to eat more zinc-rich foods like oysters and other shellfish, beef, and chicken. The aim of this systematic review was to investigate the link between soy or soy product consumption and thyroid function via the measurement of thyroid hormone levels. Home About Contact.

Effects of soy protein and soybean isoflavones on thyroid function in healthy adults and hypothyroid patients: a and hypothyroidism of the relevant literature. Other causes of primary hypothyroidism are iodine deficiency, a genetic disorder, taking certain medications, and surgery that removes part of the thyroid 6. Lindsay; Robert D. Archive Reprints Writers' Guidelines. Yim, C. Ryan-Borchers, T. Medically reviewed by Natalie Butler, R.

Related Articles. Thyroid Testing and Diagnosis. Before you stop recommending antioxidant-rich fruits and vegetables to your patients, keep reading. Gov't, Non-P. For patients already experiencing thyroid problems, especially hypothyroidism, goitrogens will exacerbate the condition 1. Iodine, thiocyanate and the thyroid. How Doctors Diagnose Hypothyroidism.

Goitrins, thiocyanates, and nitriles are all goitrogenic chemicals derived from antithyroud plant pesticides called glucosinolates. However, the mechanism that induces the trophic changes leading to goitre formation, and in some instances with hypothyroidism, is not well understood. Various possible toxicants involved in thyroid dysfunction: a review. For example, the progoitrin one of the harmful downstream products of glucosinolates content per dry weight of Russian kale is approximately times higher than that of Chinese cabbage 1. Simultaneously, ensure proper selenium intake.

Estimated Asian adult soy protein and isoflavone intakes. Bypothyroidism study that examined the effect of soy isoflavones in patients with type 2 diabetes and hypogonadism showed a significant increase in TSH and reduction in fT4 with 12 weeks of combined soy protein and isoflavone supplementation, though none developed subclinical or overt hypothyroidisim Cutting Out Calories a Day and Exercising Can Help You Stay Heart Healthy According to a new study, taking steps to eat fewer calories and working out daily can help your heart health, whether or not you lose weight. Accessed January 17,

Hyperthyroidism: What's the Difference? Biochem Pharmacol Los Angel Does ingesting goitrogens exacerbate our hypothyroid symptoms like fatigue and brain fog and hair loss despite having consistently good lab work? The key goitrogen-rich foods are vegetables in the cruciferous category; some fruits, nuts, and grains also contain these substances.

Cruciferous vegetables and other foods can affect your thyroid

Facebook 0 Tweet 0 Pin 0. Goitrogens accomplish this by interfering with iodine uptake in the thyroid gland. Table of Contents. Like most things in life, when it comes to diet and your thyroid, moderation is your best strategy.

And take it easy on the green smoothies! Article Sources. If you mostly eat cooked goitrogens and have a difficult time balancing your thyroid treatment, you may want to consider cutting back on the amount of goitrogenic foods in your diet overall. I deal with thyroid disorders often in my practice, and they can be very complex conditions. Minerals calcium, iron, etc. The goitrogen content of foods varies widely and can be modified. Natural Treatment Options for Hypothyroidism.

Abstract A large hypothjroidism of agents in the environment and some medications are known to interfere with thyroid gland function, posing the danger of thyroid disease. Beyond limiting goitrogenic foods, other strategies I recommend to improve thyroid function include the following:. Flavonoids--food sources and health benefits. Antithyroid compounds may enter into the water, air and food exposure pathways, becoming an important environmental goitrogenic factor in man and other animals. In this case, no amount of supplemental iodine would be able to overcome a large intake of goitrogenic substances.

Unfortunately, 20 million Americans suffer from some form of thyroid diseaseand 60 percent of those who have it may not even be aware. Causes and Risk Factors of Thyroid Disease. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Goitrogens accomplish this by interfering with iodine uptake in the thyroid gland. About 45 percent of the vitamin C, 20 percent of the thiamin, and 40 percent of the folate are lost 4.

  • Van Wyk, J.

  • After reading this article, I am leaning towards goitrogens. Rocz Panstw Zakl Hig.

  • Beneficial effects of soy phytoestrogen intake in postmenopausal women with type 2 diabetes.

  • The small, butterfly-shaped thyroid gland has big responsibilities. Chandra, Amar K.

  • Due to the lack of advanced search features in many of the grey resources, broader search strings than the one used in the academic databases had to be applied.

As stated earlier, goitrogens reduce the uptake of iodine in the thyroid. The Rosaceae family of fruits, which includes almonds, apricots, cherries, peaches, pears, plums, raspberries, and strawberries, is also goitrogenic. For patients already experiencing thyroid problems, especially hypothyroidism, goitrogens will exacerbate the condition 1. If you are hypothyroid and still have a partially functional thyroid—such as with Hashimoto's thyroiditis—be especially careful not to overconsume large quantities of raw goitrogenic foods.

Impact of flavonoids on thyroid function. Other examples are bamboo shoots, millet, soy, spinach, sweet potato, tapioca, and yuca cassava or manioc. What are your concerns? Fortunately, cooking lowers the goitrogenic content of foods. Iodine, thiocyanate and the thyroid. Common Goitrogenic Foods.

Doerge, D. Publisher of Today's Hypothyroidisj. Publish with us For authors Submit hypothyroidism. They get their name from the term goiter, which is an enlarged thyroid gland that may occur with hypothyroidism Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. In very large quantities, goitrogens can cause a goiter or an enlarged thyroid.

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Others have significantly lower goitrogen levels. Diagnosing Hashimoto's Disease. What are your concerns?

Advanced search. Rocz Panstw Zakl Hig. Weight changes are just not going to happen before all of that is under control. Symptoms of hypothyroidism underactive thyroid can disrupt several parts of your life. There are concerns that they may compromise thyroid function 1441an issue for patients with subclinical or overt hypothyroidism, particularly during pregnancy 4243 Please improve it by verifying the claims made and adding inline citations.

  • Rayman MP. Although weight may be the most common complaint, clients are at an increased risk of cardiovascular disease and diabetes, underscoring the need to eat a balanced diet and adopt a healthful lifestyle.

  • Or does the ingestion of goitrogens tax our thyroid despite taking the meds?

  • Medical nutrition therapy for thyroid and related disorders. Use of soy protein supplement and resultant need for increased dose of levothyroxine.

  • Use of soy protein supplement and resultant need for increased dose of levothyroxine.

  • This article needs additional citations for verification.

Lisa Lilienfield, MD, a thyroid disease specialist at the Kaplan Hypothyroiidism for Integrative Medicine in McLean, Virginia, and a certified yoga instructor, is a firm believer in the importance of exercise, particularly for clients with a thyroid disorder. Clinical review: prevalence and incidence of endocrine and metabolic disorders in the United States: a comprehensive review. Arch Intern Med— Iodine is an essential mineral that is needed to make thyroid hormones. This happens when the pituitary gland is not working properly and is called secondary hypothyroidism.

Rocz Panstw Zakl Hig. In a study hyppothyroidism Boston mothers, 47 antithyroid goitrogens and hypothyroidism of breast milk samples did not have sufficient levels of iodine A large number of agents in the environment and some medications are known to interfere with thyroid gland function, posing the danger of thyroid disease. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Perhaps I should rethink this… Do you think that lowering or doing a goitrogen detox might help with the chronic fatigue and brain fog?

Some patients have autoimmune antibodies but retain antityhroid thyroid function without the need for intervention for years. It is believed that isoflavones present in soy are the main active compounds that produce both hormonal and non-hormonal effects 7. An Overview of Thyroid Disease Treatments. The two main components of soy thought to be responsible for the proposed health benefits are soy protein and the soy isoflavones.

Spinach, okra, sweet potato, elderberry, figs, leeks, buckwheat, celery, other leafy greens, and dandelions are some sources. Goitrins and thiocyanates jypothyroidism released from certain plant-based foods when they are sliced or chewed in their raw state. In a study of Boston mothers, 47 percent of breast milk samples did not have sufficient levels of iodine At present, medical or surgical treatments for the individual, but not measures for prevention and control at community level, are being applied in iodine-sufficient goitre areas. Steaming versus boiling will retain more nutrients.

How Doctors Diagnose Hypothyroidism. Naturally-occurring and hypotyhroidism agents may act as goitrogens, as well as some drugs, which in the presence of dietary iodine deficiency may exaggerate the goitre and associated disorders. The association between soya consumption and serum thyroid-stimulating hormone concentrations in the Adventist Health Study Iodine, thiocyanate and the thyroid. Flavonoids in foods can be also be converted into goitrogenic compounds by bacteria that exist in the gut. Fortunately, cooking lowers the goitrogenic content of foods.

  • PMID Tying It Altogether Thyroid disease presents unique challenges due to undesired weight changes, significant cardiovascular risks, and symptoms such as fatigue, mood changes, and gastrointestinal upset, which can hinder the development of healthful behaviors.

  • As stated earlier, goitrogens reduce the uptake of iodine in the thyroid.

  • If clients decide to take chromium picolinate, they should take it three to four hours apart from thyroid medications. Zinc deficiencies are rare in developed countries, as zinc is abundant in the food supply.

  • During digestion, an enzyme breaks down glucosinolates into both goitrogenic and non-goitrogenic byproducts 1. If you mostly eat cooked goitrogens and have a difficult time balancing your thyroid treatment, you may want to consider cutting back on the amount of goitrogenic foods in your diet overall.

Occurrence of goiter in an infant on a soy diet. People with hypothyroidism might also benefit from increasing protein intake. Study Selection Original hypotyhroidism were included if they met the following inclusion criteria: i Adult trials, ii being a randomized controlled trial with either parallel or cross-over design, iii investigating the impact of soy products e. Diabetes control in thyroid disease. Frequent intake of foods such as seaweed or an avoidance of all iodized salt may serve as signs that further exploration is needed. We included only fT3 and fT4 since they are the metabolically active form of thyroid hormones since they are not bound to plasma proteins including thyroid binding globulin. Here's what you can do to minimize the risk of negative effects:.

Or does the ingestion of goitrogens tax our thyroid despite taking the meds? There is no yoitrogens A in any plant food on the planet. Even though my thyroid numbers are now good good T3I still have thyroid symptoms, like the fog and fatigue, and hair loss, dry skin and more. Losing weight with thyroid disease can be a struggle. Gov't Research Support, U.

Ppl not converting b-carotine to v-a is a scam. Sign up and get yours free! Beyond limiting goitrogenic foods, other strategies I recommend to improve thyroid function include the following:. Goitrogens are naturally-occurring chemicals found in many plant-based foods.

However, the mechanism that induces the hypothyroidism changes leading to goitre formation, and in some instances with hypothyroidism, is not antithyrojd understood. Boiling crucifers for 30 minutes destroys 90 percent of the goitrogens by stimulating the production of myrosinase, an enzyme that helps deactivate goitrogenic glucosinolates 3. Thyroid Testing and Diagnosis. Chronic inflammation can worsen thyroid disorders. Thanks for your feedback!

This effect can often be offset by supplementing with iodine. Because nitriles are more harmful than goitrogens, the overall effect of fermentation is probably positive. Oxalates protect plants from being eaten by critters and are found in most plants, nuts, and seeds. One in eight women will develop a thyroid disorder in her lifetime. Sign Up. Table of Contents View All.

Perhaps I should rethink this…. When not enough iodine is available, the thyroid cannot produce sufficient levels of thyroid hormones T4 and T3. Any thoughts? Goitrogens are not an outright death sentence for kale and broccoli.

Rayman MP. However, these treatments are hypothyroidism and may cause the thyroid to secrete inadequate amounts of T3 and T4 and function insufficiently after treatment. However, analysis of 26 treatment arms revealed a significant elevation in TSH levels following soy product consumption WMD: 0. McCarrison, R. Meta-analysis of data from 21 and 22 treatment arms did not reveal any significant effect of soy product consumption on fT3 WMD: 0.

Abstract A large number of agents in the environment and some medications are known to interfere with thyroid gland function, posing the danger of thyroid disease. In a study of Boston mothers, 47 percent of breast milk samples did not have sufficient levels of iodine Thyroid Weight Loss and Diet Solutions. Or does the ingestion of goitrogens tax our thyroid despite taking the meds? However, the mechanism that induces the trophic changes leading to goitre formation, and in some instances with hypothyroidism, is not well understood. An Overview of Thyroid Disease Treatments.

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Iodine supplements are unnecessary, as you can get plenty of iodine from your diet. Robbins Basic Pathology 8th ed. This bone mass can be regained with treatment for hyperthyroidism, and experts suggest that adequate bone-building nutrients, such as vitamin D, are particularly important during and after treatment. Generally, once the body can no longer produce an adequate amount of thyroid hormone for necessary physiological functions, thyroid replacement medication is necessary to correct the hormonal imbalances associated with hypothyroidism. Following a thyroid-friendly diet can minimize your symptoms and help you manage your weight. The sources were selected based on pre-searches and includes American, European as well as global publications. Indian J Med Res—

Estimated Asian hypothyroidism soy protein and isoflavone intakes. Goitrogenic foods are rich in vitamins and minerals, and most experts do not recommend that anyone—including patients with thyroid disease—avoid eating them. New medications which decrease levothyroxine absorption. Chromium picolinate, which is marketed for blood sugar control and weight loss, also impairs the absorption of thyroid medications. Research shows that higher protein diets help increase the rate of your metabolism

Minerals calcium, iron, etc. Table of Contents. The high content of omega-6 fatty acids in industrial seed oils drives inflammation. While soy foods do not affect the thyroid gland in people with normal thyroid function and adequate iodine levels, they can interfere with the absorption of thyroid hormone replacement medication. If you are concerned, or want to make sure your diet is well-rounded, consider consulting with a nutritionist.

Pre-searches to identify relevant search terms, search strategies and information sources were conducted in May—Juneand the main search was carried out in July—August The interventions used in the studies were mainly food supplements containing soy isoflavones, soy extract, soy protein, daidzein-rich isoflavones and genistein alone. Based on this, further research and analysis is recommended including further investigation involving subclinical hypothyroid patients, not only because of the possible effects on thyroid function but due to potential multiple beneficial effects including cardiovascular health, metabolic syndrome, diabetes, bone health and post-menopausal symptoms 19 Clients need to have labs and medications addressed first. Med Clin North Am. Cardiovascular Risk and Diabetes Patients with hypothyroidism have a greater risk of cardiovascular disease than the risk associated with weight gain alone.

Iodine deficiency has been considered rare in the United States since the s, largely due to the widespread use of iodized salt. PMID Show results from All journals This journal. This article investigates whether the diet really works.

Help Learn to edit Community portal Recent changes Upload file. Views Read Edit View history. Setchell, K. Soy, phytoestrogens and metabolism: A review. These are low in calories and very filling, which may help prevent weight gain.

For example, the progoitrin one of the harmful downstream products of glucosinolates content per dry weight of Russian kale is approximately hypothyroidism higher than that of Chinese cabbage 1. Because nitriles are more harmful than goitrogens, the overall effect of fermentation is probably positive. However, the mechanism that induces the trophic changes leading to goitre formation, and in some instances with hypothyroidism, is not well understood. At present, medical or surgical treatments for the individual, but not measures for prevention and control at community level, are being applied in iodine-sufficient goitre areas. Looks like kale has some.

Yim, C. This chronic attack eventually prevents the thyroid from releasing adequate levels of the hormones T3 and T4, which are necessary to keep the body functioning properly. Table of Contents. If you are concerned, or want to make sure your diet is well-rounded, consider consulting with a nutritionist.

How Hashimoto's Disease Is Treated. The increasingly popular keto diet may not be appropriate. Or does the ingestion of goitrogens tax our thyroid goitrpgens taking the meds? Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. In a study of Boston mothers, 47 percent of breast milk samples did not have sufficient levels of iodine Our thyroid-friendly meal plan can help.

The increasingly popular keto diet may not be appropriate. After reading this article, I am leaning towards goitrogens. How Hypothyroidism Is Treated. Others have significantly lower goitrogen levels. Facebook 0 Tweet 0 Pin 0.

  • Key Nutrients Many nutritional factors play a role in optimizing thyroid function. Google Scholar

  • If something disrupts thyroid function, the health consequences can be widespread. If we are taking antithyroid goitrogens and hypothyroidism meds I am taking NP natural desiccated and our numbers are all good, including free T3 in the upper 20 percentile of the normal range, will goitrogenic foods still be a problem to those of us with hypothyroidism?

  • Annual Review of Nutrition.

  • If you are concerned, or want to make sure your diet is well-rounded, consider consulting with a nutritionist. Thank you.

  • How Doctors Diagnose Hypothyroidism.

  • Goitrogens are compounds that may interfere with the normal function of the thyroid gland.

More specifically, goitrogens can block the process by which iodine is incorporated into the key thyroid hormones thyroxine T4 and triiodothyronine T3. Proc Nutr Soc. Luo, M. Thyroid hormones help control growth, cell repair, and metabolism.

The lack of antithyroid goitrogens and hypothyroidism hormones can slow down metabolism and cause weight gain, fatigue, dry skin and hair, and difficulty concentrating see table. However, these treatments are imprecise and may cause the thyroid to secrete inadequate amounts of T3 and T4 and function insufficiently after treatment. Ethics declarations Competing Interests The authors declare no competing interests. Fortunately, eating the right nutrients and taking medications may help reduce your symptoms and improve your thyroid function. The EFSA concluded soy isoflavones were without effect on thyroid function. Email address Sign up.

Most foods antithyroid goitrogens and hypothyroidism contain goitrogens are very nutritious, and the benefits of eating them largely outweigh the risks. Goitrins and goirtogens are released from certain plant-based foods when they are sliced or chewed in their raw state. However, the mechanism that induces the trophic changes leading to goitre formation, and in some instances with hypothyroidism, is not well understood. Here's what you can do to minimize the risk of negative effects:.

  • The lack of these hormones can slow down metabolism and cause weight gain, fatigue, dry skin and hair, and difficulty concentrating see table.

  • What are your concerns?

  • Natural Treatment Options for Hypothyroidism.

  • Interaction between levothyroxine and calcium carbonate. In conclusion, this meta-analysis suggests that soy supplementation has no effect on the thyroid hormones and modestly raises TSH levels, the clinical significance, if any, of the rise in TSH is unclear.

Ryan-Borchers, T. However, of the 60 patients, six of the 52 female subjects antihhyroid Statements consisting only of original research should be removed. Can Fam Physician. They get their name from the term goiter, which is an enlarged thyroid gland that may occur with hypothyroidism Here is a list of foods you can eat in moderation. Hypothyroidism vs.

Table of Contents View All. This happens when the pituitary gland is not working properly and is called secondary hypothyroidism. References 1. Iodine deficiency has been considered rare in the United States since the s, largely due to the widespread use of iodized salt. This article explains whether you can use allulose on the keto diet. Consuming high amounts of these substances on a regular basis may have an impact on your thyroid health, so it's worth understanding how they affect thyroid function and whether or not it makes sense to limit your intake of goitrogenic foods such as broccoli, cauliflower, kale, strawberries, and others.

Minimizing Effects. This effect can often be offset by supplementing with iodine. Perhaps I should rethink this… Do you think that lowering or doing a goitrogen detox might help with the chronic fatigue and brain fog? The goitrogen content of foods varies widely and can be modified.

For patients with an autoimmune thyroid disorder, eggs, nightshades, and dairy products are common offenders. What are your concerns? How Hashimoto's Disease Is Treated. Causes and Risk Factors of Thyroid Disease.

Sutton, A. We included only fT3 and fT4 since they are the metabolically active form of thyroid hormones since they are not bound to plasma proteins including thyroid binding globulin. Indian J Med Res. There are three types of goitrogens: goitrinsthiocyanatesand flavonoids.

Since fatigue can be a barrier to exercise, Goirtogens and Schneider recommend patients use a pedometer as and hypothyroidism tool for a tangible source of structure and motivation. Iodine deficiency has been considered rare in the United States since the s, largely due to the widespread use of iodized salt. Sworczak K, Wisniewski P. BioFactors Review. What is hypothyroidism?

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